All Might and Deku accept an invitation to go abroad to a floating and mobile manmade city, called 'I Island', where they research quirks as well as hero supplemental items at the special 'I Expo' convention that is currently being held on the island. During that time, suddenly, despite an iron wall of security surrounding the island, the system is breached by a villain, and the only ones able to stop him are the students of Class 1-A.
Somewhere in Tokyo, there is a room. In that room is a black sphere. Periodically, people who should otherwise have died are transferred to the room. There, the sphere gives them special suits and weapons, and sends them out on a mission to kill aliens here on Earth. While these missions take place, the rest of the world is largely oblivious to them. These missions are lethal - few participants survive them. The sphere calls the shots, and it's not the slightest bit nice. Its name... Gantz.