Captain Jack Sparrow crosses paths with a woman from his past, and he's not sure if it's love -- or if she's a ruthless con artist who's using him to find the fabled Fountain of Youth. When she forces him aboard the Queen Anne's Revenge, the ship of the formidable pirate Blackbeard, Jack finds himself on an unexpected adventure in which he doesn't know who to fear more: Blackbeard or the woman from his past.
Depression-era bank robber John Dillinger's charm and audacity endear him to much of America's downtrodden public, but he's also a thorn in the side of J. Edgar Hoover and the fledgling FBI. Desperate to capture the elusive outlaw, Hoover makes Dillinger his first Public Enemy Number One and assigns his top agent, Melvin Purvis, the task of bringing him in dead or alive.
A 14th century Crusader returns with his comrade to a homeland devastated by the Black Plague. The Church commands the two knights to transport a witch to a remote abbey, where monks will perform a ritual in hopes of ending the pestilence.